According to the Food and Agriculture Organization’s AMR action plans (2016–2020), AMR affects every sector and actor, regardless of economic status or geographic location. Preferred Reporting Items for Systematic Reviews and Meta-AnalysesĪntimicrobial resistance (AMR) is the ability of microorganisms to become increasingly resistant to an antimicrobial drug to which they were previously susceptible, resulting in infections persisting in the body and increasing the risk of spreading to the human and animal population through food, water, and the environment. Knowledge, attitudes and practices PRISMA, This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.ĭata Availability: All relevant data are within the manuscript and its Supporting Information files.įunding: The author(s) received no specific funding for this work.Ĭompeting interests: The authors have declared that no competing interests exist Received: MaAccepted: Published: June 9, 2023Ĭopyright: © 2023 Woldegeorgis et al. PLoS ONE 18(6):Įditor: Mohammed Feyisso Shaka, Madda Walabu University, ETHIOPIA As a result, we call for greater educational interventions to raise awareness and build a strong national AMR narrative.Ĭitation: Woldegeorgis BZ, Kerbo AA, Obsa MS, Mokonnon TM (2023) A systematic review and meta-analysis of antimicrobial resistance knowledge, attitudes, and practices: Current evidence to build a strong national antimicrobial drug resistance narrative in Ethiopia. In conclusion, there is a significant knowledge and practice gap on AMR among the general public, patients, and livestock producers. The pooled prevalence of favorable attitudes and good practices were 63.43%, and 48.85% respectively. Overall, the pooled prevalence of good AMR knowledge was 51.53%. Fourteen studies with a total of 4476 participants met the inclusion criteria. In addition, sensitivity and subgroup meta-analyses were performed. Publication bias was investigated by funnel plots, and the regression-based test of Egger for small study effects with a P value < 0.05 was considered to indicate potential reporting bias. Statistical heterogeneity of the meta-analysis was checked through Higgins and Thompson’s I 2 statistics and Cochran’s Q test. The random-effect meta-analysis model was used to estimate Der Simonian-Laird’s pooled effect. The methodological quality of the studies included was assessed by the Joana Briggs Institute critical appraisal checklists. The Preferred Reporting Items for Systematic Reviews and Meta-Analysis 2020 checklist was followed.
SCP META NARRATIVE SOFTWARE
Microsoft Excel spreadsheet and STATA software version 16 were used for data extraction and analysis, respectively.
Articles were searched in international electronic databases.
Given the rising prevalence of AMR, which is expected to pose a challenge to current empirical antibiotic treatment strategies, we sought to summarize the available data on knowledge, attitudes, and practices regarding AMR in Ethiopia. Antimicrobial resistance (AMR) is a silent pandemic that has claimed millions of lives, and resulted in long-term disabilities, limited treatment options, and high economic costs associated with the healthcare burden.
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